Israeli Prime Minister, Benjamin Netanyahu, said on Saturday that the joint US-Israeli campaign against Iran has succeeded in “crushing” the Islamic republic’s nuclear and ballistic missile programmes.

Netanyahu’s comments came as Iranian and US officials held two rounds of face-to-face talks in Pakistan in a bid to end the Middle East war, with a third round expected later on Saturday evening or Sunday, Iranian state television reported.

“We have succeeded in crushing the nuclear programme, and crushing the missile programme,” Netanyahu said in a televised statement, adding that the war against Tehran had also weakened Iran’s leadership and its regional allies.

“We have reached a situation in which Iran no longer has a single functioning enrichment facility.”

Netanyahu said the United States and Israel had prevented Iran from acquiring a nuclear bomb by launching a war in June 2025, followed by the current campaign that began on February 28.

He said the latest war was launched after intelligence indicated that the now deceased Iranian supreme leader Ali Khamenei had sought to expand the country’s nuclear and missile programmes even after the June 2025 war.

“He sought to bury both missile production and nuclear production deep, deep beneath a mountain, in a way that even B-2 aircraft could not reach. Once again, we could not stand by. We acted,” Netanyahu said.

“Most of its missile production capacity has disappeared. They still have missiles, they still have stockpiles, but it is shrinking.”

He said there were “enormous achievements” in the war effort.

“They are reflected in this weakened regime, which is now even seeking a ceasefire,” he said.

Netanyahu added that, for decades, Iran’s leadership and its allies had threatened Israel.

“They wanted to strangle us, and (now) we are strangling them. They threatened us with annihilation, and now they are fighting for survival.”

On Lebanon, Netanyahu said the country had approached Israel regarding a potential peace deal.

“In the past month, it has reached out several times to begin direct peace talks,” Netanyahu said.

“I have given my approval, but on two conditions: we want the dismantling of Hezbollah’s weapons, and we want a real peace agreement that will last for generations.”

On Friday, Lebanon’s presidency said that a meeting would be held with Israel in Washington next week to discuss a ceasefire in the Israel-Hezbollah war and the potential start of negotiations between the neighbours.

Hezbollah and Israeli forces have been clashing since March 2, two days after the start of the Iran war, following rocket fire by the Lebanese armed group at Israel in retaliation for the killing of Khamenei.

Since then, Israel has killed at least 2,020 people in Lebanon, including 248 women, 165 children and 85 medical and emergency personnel, according to the Lebanese health ministry.

Israel carried out its largest air attack this week on Lebanon since March 2, which it says left hundreds of Hezbollah fighters dead.

Even as Netanyahu spoke, around 800 Israeli protesters rallied in Tel Aviv on Saturday to protest against the wars in Iran and Lebanon, accusing Netanyahu of attempting to derail the ceasefire with Iran.

“In Bibi, we don’t trust,” read one banner, using Netanyahu’s nickname, as protesters chanted: “No to endless wars, no to a government of death”.

Protester Martin Goldberg said Netanyahu was not in favour of a ceasefire with Iran.

“What happened immediately after the ceasefire in Iran, Israel launched one of its largest attacks in Lebanon, which in my opinion, was an attempt to try and sabotage the ceasefire with Iran,” the 61-year-old demonstrator told AFP.

“Israel is pretty openly saying that they’re not interested in a ceasefire in Iran, and they don’t want a peaceful solution in Iran.”

Iran, on Wednesday, shut the Strait of Hormuz following fresh Israeli strikes on Hezbollah targets in Lebanon, raising fears that a fragile ceasefire with the United States could collapse less than a day after it was reached.

The closure comes amid renewed hostilities that have cast doubt over efforts to halt more than a month of fighting. While both Iran and the United States had earlier declared victory after brokering the truce, fresh missile and drone attacks were reported across Iran and parts of the Gulf, alongside intensified Israeli bombardments in Lebanon.

In Beirut, Israeli strikes hit residential and commercial areas without prior warning, leaving at least multiple people dead and many others injured in what has been described as one of the deadliest days of the conflict.

Iranian state media confirmed the closure, with IRNA reporting that the move was taken “in the wake of Israel’s attacks on Lebanon.” The development has heightened concerns over the stability of the ceasefire agreement mediated by the United States.

Authorities in Iran also imposed strict controls on maritime movement in the strategic waterway. Ships near the strait were instructed to seek permission from Sepah, a special operations unit under the Iranian Revolutionary Guard Corps, before passage. A radio message cited by The Wall Street Journal warned that any vessel attempting to cross without approval “will be destroyed.”

Earlier in the day, Iran had indicated a willingness to reopen the strait during the proposed two-week ceasefire, noting this would be done with “coordination with Iran’s Armed Forces and with due consideration of technical limitations.” U.S. officials, meanwhile, said American forces could assist in managing ship traffic, although details remain unclear.

U.S. President Donald Trump also told ABC News he was open to a “joint venture” arrangement with Iran that would involve charging tolls for vessels passing through the strait.

However, reports of ceasefire breaches soon emerged. Pakistani Prime Minister Shehbaz Sharif, who played a role in negotiating the agreement, said on X that violations had already been recorded, further deepening uncertainty over whether the truce will hold.

Israeli authorities are investigating a missile strike in central Tel Aviv that may have involved a weapon breaking into several parts before impact.

The Israeli government’s press office described the incident as a direct hit from a ballistic missile.

A police commander in the Tel Aviv area also told a local Israeli television station that the impact involved what he described as a “splitting missile.”

The description has raised the possibility that the weapon may have been a type of cluster munition. These weapons contain smaller explosive “bomblets” that separate from the main missile and spread across a wider area after the initial explosion.

Israel has previously accused Iran of using similar munitions earlier in the conflict and during the 12-Day War last June.

Cluster munitions are banned by more than 100 countries under the Convention on Cluster Munitions, although Iran, Israel and the United States are not signatories to the treaty.

At the scene of the explosion in Tel Aviv, a CNN reporter said investigators are examining debris believed to be part of the missile.

“Debris still falls in central Tel Aviv even after interceptions. One key piece behind me here that investigators are poring over, one official here telling us that it seems to perhaps be one of the warheads we’ve noticed that appear to split in the sky and send off separate fragments down. Now nobody as far as we understand injured in this location but it’s a sign that despite the fact we’ve seen probably less missiles overall fired by Iran over the past days, it only takes one even with the sophisticated air defences here to cause some havoc in a scene like this.”

The reporter, in to a CNN video, added that the strike has drawn attention from investigators trying to determine whether the weapon signals a change in Iran’s missile capabilities.

“But across the region the focus perhaps now turning as it’s clear Iran’s missile capacities have come down on their ability to wreak havoc closer to Iranian shores with drones that are hitting around the but the scene behind me here is still one of intense scrutiny as I think they try and work out if this marks some kind of new development in Iranian missile technology.”