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Moderna: COVID Vaccine Shows Nearly 95% Protection

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A new vaccine that protects against Covid-19 is nearly 95% effective, early data from US company Moderna shows.

The results come hot on the heels of similar results from Pfizer, and add to growing confidence that vaccines can help end the pandemic.

Both companies used a highly innovative and experimental approach to designing their vaccines.

Moderna says it is a “great day” and they plan to apply for approval to use the vaccine in the next few weeks.

However, this is still early data and key questions remain unanswered.

How good is it?

The trial involved 30,000 people in the US with half being given two doses of the vaccine, four weeks apart. The rest had dummy injections.

The analysis was based on the first 95 to develop Covid-19 symptoms.

Only five of the Covid cases were in people given the vaccine, 90 were in those given the dummy treatment. The company says the vaccine is protecting 94.5% of people.

The data also shows there were 11 cases of severe Covid in the trial, but none happened in people who were immunised.

“The overall effectiveness has been remarkable… it’s a great day,” Tal Zaks, the chief medical officer at Moderna, told BBC News.

Dr Stephen Hoge, the company’s president, said he “grinned ear to ear for a minute” when the results came in.

He told BBC News: “I don’t think any of us really hoped that the vaccine would be 94% effective at preventing Covid-19 disease, that was really a stunning realisation.”

When will I get it?

That depends on where you are in the world and how old you are.

Moderna says it will apply to regulators in the US in the coming weeks. It expects to have 20 million doses available in the country.

The company hopes to have up to one billion doses available for use around the world next year and is planning to seek approval in other countries too.

The UK government is still negotiating with Moderna as their vaccine is not one of the six already ordered. It says Moderna’s will not be available before spring next year.

The UK has outlined plans that prioritise the oldest people for immunisation.

What don’t we know?

We still do not know how long immunity will last as volunteers will have to be followed for much longer before that can be answered.

There are hints it offers some protection in older age groups, who are most at risk of dying from Covid, but there is not full data.

Mr Zaks told the BBC their data so far suggests the vaccine “does not appear to lose its potency” with age.

And it is not known whether the vaccine just stops people becoming severely ill, or if it stops them spreading the virus too.

All these questions will affect how a coronavirus vaccine is used.

Is it safe?

No significant safety concerns have been reported, but nothing, including paracetamol, is 100% safe.

Short lived fatigue, headache and pain were reported after the injection in some patients.

“These effects are what we would expect with a vaccine that is working and inducing a good immune response,” said Prof Peter Openshaw, from Imperial College London.

How does this compare to the Pfizer vaccine?

Both vaccines use the same approach of injecting part of the virus’s genetic code in order to provoke an immune response.

The preliminary data we have seen so far is very similar – around 90% protection for the Pfizer/BioNTech vaccine and around 95% for Moderna’s.

However, both trials are still taking place and the final numbers could change.

Moderna’s vaccine appears to be easier to store as it remains stable at minus 20C for up to six months and can be kept in a standard fridge for up to a month.

Pfizer’s vaccine needs ultra-cold storage at around minus 75C, but it can be kept in the fridge for five days.

The Sputnik V vaccine, developed in Russia, has also released very early data which suggests it is 92% effective.

How does it work?

Moderna has developed an “RNA vaccine” – it means part of the coronavirus’s genetic code is injected into the body.

This starts making viral proteins, but not the whole virus, which is enough to train the immune system to attack.

It should train the body to make both antibodies – and another part of the immune system called T-cells to fight the coronavirus.

BBC

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Supreme Court Verdict: ADC Chieftain Advises Tinubu to Kiss Aso Rock Goodbye

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A chieftain of the African Democratic Congress (ADC), Eze Chukwuemeka Eze, has declared that it is over for the President Bola Tinubu administration following the Supreme Court ruling that restored the David Mark-led National Working Committee (NWC) of the opposition party.

Eze, in a statement on Friday, criticized the Attorney General of the Federation, Lateef Fagbemi (SAN) and the INEC chairman, Prof Joash Amupitan, asserting that they should be ashamed for acting as obstacles to the survival of democracy in Nigeria.

He said: “The government led by President Bola Tinubu has tarnished the judiciary. Certain judges and courts are reportedly being systematically employed to undermine the leadership of political parties in anticipation of the 2027 general elections.

“Even when all seemed lost, given the recent court rulings in political cases, particularly those involving opposition parties, Thursday’s Supreme Court judgment was a divine intervention.

“We express our gratitude to God Almighty for prompting the Supreme Court to overturn that disgraceful, distorted, and anti-democratic ruling issued by the Federal High Court, the Court of Appeal, and the misguided interpretation and decision of INEC regarding our party, the ADC.”

He stressed that the time has come for Tinubu and his alleged undemocratic associates in Aso Rock to return to Lagos.

“With Thursday’s ruling saving the ADC from destruction, it is time for Tinubu to begin drafting his handover notes and prepare for his return to Lagos State,” Eze stated.

Eze advised the ADC to concentrate on its primary function as a prominent opposition party in the upcoming 2027 general elections, as that the leadership dispute has been resolved.

He emphasized that stability at the upper levels of the party will result in improved organization, clearer communication, and enhanced participation in Nigeria’s political arena.

Notably, he asserted that the ruling will add to Nigeria’s expanding collection of case laws regarding political party governance, and urged the ADC to stay focused on its objective of reclaiming power from the APC due to poor governance.

“It highlights the judiciary’s role in interpreting party constitutions and ensuring adherence, which may affect how future conflicts are resolved,” Eze stated.

He praised the panel for upholding justice, remarking that any opposing decision regarding the ADC’s alleged leadership issue would have further entangled the Judiciary in the murky waters of arbitral corruption.

“Clearly, this ruling has set the stage for cohesion, unity, stability, and effective leadership within the ADC.

“With this issue now definitively settled, even though it should not have been justiciable ab initio, as it pertains to an internal matter of a political party, we urge all our members, stakeholders, and supporters to unite behind the David Mark-led leadership of the ADC to collectively reposition the party for greater national significance, viability, and visibility,” Eze said.

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2027: We’re on Track, ADC Hails S’Court Ruling

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The African Democratic Congress (ADC) has declared that it would never be intimidated, distracted, or silenced in its push to realize a better Nigeria.

Spokesman of the ADC, Bolaji Abdullahi, said this in reaction to the Supreme Court ruling, which affirmed David Mark’s leadership of the party.

Abdullahi said the judgment has affirmed that the Mark and Rauf Aregbesola leadership of the party is legitimate.

Abdullahi said: “The African Democratic Congress (ADC) congratulates all our members and leaders across the country on today’s Supreme Court ruling which affirmed the leadership of our party under Senator David Mark as National Chairman, and Ogbeni Rauf Aregbesola as National Secretary.

“Today’s decision is a clear affirmation that our party, its structures, and its leadership under our National Chairman, Senator Mark, and our National Secretary, Ogbeni Aregbesola, are legitimate.

“We commend the five-man panel of the Supreme Court, whose unanimous judgment has today done great credit to the judiciary in our country and our political system.

“However, while we welcome this judgment, we do not mistake it for the end of the struggle. The events leading up to this moment have exposed a troubling pattern of interference, bad faith, and attempts to weaken opposition voices in Nigeria.

“Let it be clearly stated: the ADC will not be intimidated, distracted, or silenced. We remain resolute in our mission to provide Nigerians with a credible alternative.

“We therefore urge all our members, supporters, and democratic stakeholders across the country to remain vigilant.”

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Tinubu Appoints Bianca Ojukwu As Foreign Affairs Minister

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